Microneedling Vs Botox: What’s the Best Choice? [Comparison]

Oh, my fabulous beauty enthusiasts, let’s dive into the world of Microneedling Vs Botox, where youthful skin reigns supreme!

As a devoted skincare aficionado, I can’t wait to dish the deets on these two wildly popular treatments, giving you the lowdown on which method may be your ticket to wrinkle-free bliss.

Get ready to transform your skincare game as we embark on this fun, friendly, and whimsical journey into the land of age-defying miracles.

So, grab your favorite face mask and let’s get our glow on, shall we?

Key Takeaways

  • Microneedling and Botox are both effective treatments for fine lines, wrinkles, and other skin concerns, but their mechanisms, cost, and effects differ.
  • Microneedling creates micro-injuries in the skin to stimulate collagen production, while Botox temporarily paralyzes muscles to reduce wrinkles.
  • The choice between the two treatments depends on the individual’s needs and expectations, and some people may benefit from combining both treatments for optimal results. It is important to consult a professional dermatologist to determine the best option.

What is Microneedling Good For?

The US Food and Drug Administration [1] has approved the use of Microneedling devices in people with all skin types aged 22 or above to help treat fine lines and wrinkles, acne scars, dark spots, and stretch marks and improve skin texture.

Medically called Collagen Induction Therapy, microneedling creates micro-channels in the skin through hundreds of penetrating thin needles.

lady having a microneedling session

As a result, skin cells come into action, enhancing the natural production of collagen. This collagen boost helps in the natural healing process improving skin quality.  

Microneedling can also be performed professionally or at home using derma rollers.

Check out this video for all you need to know about microneedling:

Derma roller vs microneedling, which is which? Derma Rolling is a term for microneedling performed with a derma roller manually.

Efficiently softening wrinkles and stretch marks, this therapy can be done from the comfort of your home without spending too much.

It also helps transfer topical creams and serums to the deeper layers of the skin-enhancing their effectiveness.

Dermapen, an automated device, is preferred by most dermatologists [2].

It is adjustable and should be used for more severe scarring and wrinkles to reach narrower areas of the face, such as around the lips and nose.

So what exactly is Botox, and how does it work?

What is Botox & How Does it Work? 

Botulinum toxin, or Botox, is a purified protein that temporarily relaxes muscles.

It treats various medical conditions, including excessive sweating and muscle spasms.

But it is most commonly used to remove wrinkles and prevent the development of new ones.

Botox can also be used to treat excessive underarm sweating.

lady getting a botox

How Does Botox Work?

Botulinum toxin inhibits acetylcholine release at the neuromuscular junction by binding to nerve endings in the skin and blocking impulse transmission.

When this happens, the muscles become paralyzed and no more extended contract when stimulated by nerves.

And therefore aids in minimizing frown lines, forehead furrows, and crow’s feet [3]. 

Botox is injected into specific areas on your face, such as between the eyebrows or around mouth corners where you have frown lines or crow’s feet.

The injections are quick and easy to administer by an experienced medical professional who can assess your unique needs before treatment begins!

Botox takes about three days to work its magic and create noticeable results. But once it does start working, you should see results within weeks, if not days.

Have a look at how Botox works.

How long do Botox results last 

Botox results can last anywhere from 3-to 6 months [4]. Various factors play into how long the effects last, including your skin type, where you have injections done (the forehead typically lasts longer than other areas), and the amount of Botox used.

Your lifestyle is the most significant factor in how long your Botox will last.

If you smoke, drink alcohol, or consume caffeine regularly, those things will reduce the lifespan of your Botox results.

You should also be sure to avoid sun exposure! UV rays can break down Botox as it’s injected into your skin.

So if you want to maintain those fantastic results for as long as possible, make sure to wear sunscreen every day!

lady putting on sunscreen

 Younger people also tend to maintain it for a more extended time. 

Here are some more tips you should take into account so that your Botox lasts longer

  • No facial, workout, or nap 4 hours after Botox therapy to prevent droopy eyelid.
  • No icing afterward, as temperature drops will decrease the uptake and longevity of Botox.
  • No pressing or massaging blebs to prevent the toxin from spreading elsewhere in the body.
  • Avoid alcohol consumption as it can disturb blood clotting by diminishing the platelet count and making them less adhesive. 
  • It is better to wait 30 minutes before applying makeup to prevent foreign bodies from entering your blood and causing infections.

Watch what she has to say regarding the aftercare of Botox therapy:

Although it’s a safe procedure, few people can develop injection site swelling and pain.

It may also lead to droopy eyelids, dry eyes, and mouth, crooked smiles, headaches, and flu-like symptoms. But there are usually no adverse signs after healing.

Diluting the toxin with saline significantly reduces the risk of side effects. [5]

READ MORE: What to Do After Botox?

What Is The Difference Between Microneedling & Botox? 

Both microneedling and Botox are excellent treatments for different reasons, but they both offer similar results in reducing fine lines and wrinkles.

Based on the mechanism, cost, and effects of both procedures, here is a brief comparison. 

Works by producing micro-injuries in the skin and inducing collagen production Works by inhibiting the contraction of muscles 
Affects the skin only Affects the muscles 
Occurs on a more superficial levelOccurs on a deeper level 
Softens static wrinkles Softens dynamic wrinkles 
Treats other skin conditions like Melasma, Rosacea, Stretch marks, and acne scarsTreats other muscular conditions like neck and upper limb spasms, detrusor overactivity, and eye disorders
Cost varies from $200 to $700 Price varies from $300 to $600
The procedure usually takes 30 minutes to complete The procedure usually takes 10 minutes to complete
No unnatural changes to the appearanceIt can produce unnatural changes to the appearance
Done over the whole area Site-specific 
Results are immediate Results can take a few days 
Minimal adverse effects like redness or itching Adverse effects can vary from hemorrhage to droopy eyelid and dysphagia
The next session can be taken after 30 daysThe next session should not be taken anytime before 3 months.
Can supplement the effect of other proceduresShould not be used in conjunction with any other procedure

Botox vs Micro-needling: What Should I Select 

There should be no debate about choosing one procedure over the other.

It’s like asking if everybody should opt for a dry skin foundation or an oily one. 

Silly right? 

Both treatments have pros and cons; however, if you’re looking for a more permanent, natural solution, micro-needling might be right for you! But for stubborn, deep-seated wrinkles, then Botox is for you.

While both procedures serve different purposes, you should know what you want the end product to be. Convey your expectations to your dermatologist, and then select what suits you best. 

Some people even prefer to have both treatments for better results.

Is Micro-needling Better Than Botox?

In a way, we can call Micro-needling better than Botox due to its safety, rapid results, and natural appearance. 

lady having a microneedling session

Microneedling is a newer cosmetic procedure, but it has gained immense popularity.

Botox stiffens specific muscles, ultimately increasing the workload of the remaining ones, while Micro-needling is performed over the entire area producing no stresses. 

Boosting your collagen production by microneedling will increase the efficacy of other cosmetic procedures with the added benefit of youthful skin.

On the other hand, Botox specialists at the Skin Perfection Clinic, UK [6], advise not undergoing any other cosmetic therapy after Botox for at least 14 days.

The reason lies in that it takes a few days for Botox to settle into the muscle tissue. 

Can I Receive Botox and Microneedling Together?

Absolutely, you can receive Botox and microneedling together, but there are some essential factors to keep in mind! Combining these two powerful treatments can deliver awe-inspiring results, but timing and expertise play a crucial role in ensuring a successful outcome.

Botox, the wrinkle-busting injectable, works by temporarily relaxing facial muscles, reducing the appearance of fine lines and wrinkles.

Microneedling, on the other hand, uses tiny needles to create micro-channels in your skin, promoting collagen production and overall skin rejuvenation.

Now, let’s talk timing! While both treatments can be performed in the same appointment, it’s crucial to consult with a skilled professional who can determine the best approach for your unique needs.

In some cases, it might be beneficial to space the treatments out by a week or two to allow your skin to heal and respond to each treatment individually.

Safety is paramount, my darlings! Be sure to choose a reputable, experienced practitioner who understands the nuances of combining these treatments.

They’ll assess your skin’s condition, your desired results, and any potential risks before creating a customized plan tailored just for you.

In conclusion, while Botox and microneedling can be a fabulous dynamic duo for tackling skin woes, it’s crucial to work closely with a trusted professional to ensure you achieve the glowing, youthful complexion of your dreams!

So, go ahead and explore the possibilities, but remember: your skin is your canvas, and it deserves the utmost care!


How long after microneedling can I get Botox?

You can get Botox immediately after microneedling. However, most experts believe taking a 3-5 days gap is better.

How long after Botox can I get Microneedling? 

After Botox, at least 7-14 days must be spared before undergoing any cosmetic procedure, including microneedling.

Can Microneedling replace Botox?

No. Both are separate procedures, and they can supplement each other, but one cannot substitute the other. 


Microneedling vs. Botox, which is best? While both procedures can be used for similar purposes, the results differ dramatically. I hope this article has helped you decide which procedure is right.

It’s vital to consult a professional dermatologist, as no one likes to play around when it comes to your skin. 

lady getting a botox

Do you prefer microneedling or Botox? Please share below!


  • 1. Health C for D and R. Microneedling Devices. FDA. Published online November 9, 2020. Accessed May 17, 2022. https://www.fda.gov/medical-devices/aesthetic-cosmetic-devices/microneedling-devices#:~:text=The%20FDA%20has%20legally%20authorized
  • 2. Yadav S, Singh A. Microneedling: Advances and widening horizons. Indian Dermatology Online Journal. 2016;7(4):244. doi:10.4103/2229-5178.185468
  • 3. HIGHLIGHTS of PRESCRIBING INFORMATION These Highlights Do Not Include All the Information Needed to Use BOTOX ® Safely and Effectively. See Full Prescribing Information for BOTOX. BOTOX (OnabotulinumtoxinA) for Injection, for Intramuscular, Intradetrusor, or Intradermal Use Initial U.S. Approval: 1989 _________________________ RECENT MAJOR CHANGES.; 2017. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/103000s5302lbl.pdf
  • 4. Mayo Clinic. Botox injections – Mayo Clinic. Mayoclinic.org. Published 2019. https://www.mayoclinic.org/tests-procedures/botox/about/pac-20384658
  • 5. Witmanowski H, Błochowiak K. The whole truth about botulinum toxin – a review. Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii. 2020;37(6):853-861. doi:10.5114/ada.2019.82795
  • 6. Can you get microneedling after botox? Skin Perfection. Published November 19, 2021. Accessed May 17, 2022. https://www.skinperfectionlondon.co.uk/2021/11/can-you-get-microneedling-after-botox/#:~:text=Your%20botox%20needs%20up%20to
About Olaf Bieschke

Olaf Bieschke is a senior year medical student from Charité University of Berlin in Germany. He has gained professional experience in various hospitals and offices in Germany, Belgium, France, Poland, Brazil and Spain. Currently working on a dr. med. title thesis in neurosurgery. Follow him on LINKEDIN AND FACEBOOK. Learn more about him HERE.

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